The Guthrie Clinic is a non-profit integrated health system serving north-central Pennsylvania and upstate New York. Headquartered in Sayre, Pennsylvania, Guthrie operates five hospitals (Sayre, Towanda and Troy, PA and Corning and Cortland, NY) and a large multispecialty group practice — one of the first in the United States — with roughly 500 physicians and providers across more than 47 specialties. Its flagship, Guthrie Robert Packer Hospital, is a Level II regional trauma center.